Endocrine Abstracts

Background and objective: The incidence of differentiated thyroid carcinoma (DTC) is increasing worldwide. Radioiodine (RAI) ablation is one of the main elements in the therapy of DTC after surgical removal of the gland. This study aims to compare the use of I131 in a Spanish Cohort of DTC before and after the American Thyroid Association (ATA) 2009 guidelines.Patients and methods: The Cadit-CAM study was designed to evaluate retrospectively characterist...

Background: The main limitation of fine-needle aspiration (FNA) is represented by indeterminate category (Bethesda III and IV) in which the risk of malignancy is between 5-30%. Given this result, surgical treatment is necessary in many cases. The aim of our study is to assess whether the ultrasound patterns proposed by the ATA, help us to stratify the risk of malignancy in nodules with Bethesda IV cytology result.Methods: From January 2011 to June 2017 w...

Objetive: The aim of our study is to asses the validity of ultrasound patterns proposed by the ATA and malignancy risk in the cytological diagnosis classified by the Bethesda System.Methods: Prospective study including all thyroid nodules (with no previous cytological results), assessed in our center from July/2016 to June/2017. We classified nodules in ATA sonographic risk patterns and follow-up its fine needle aspiration (FNA) recommendations. The stat...

Introduction, material and methods: The BRAF isoform of RAF has been implicated in the pathogenesis of papillary thyroid cancer, but not of benign or follicular neoplasms. Also, BRAF mutations may confer a worse clinical prognosis than for papillary thyroid cancer without the BRAF mutation. Recurrence occurs more frequently when BRAF mutations are present. In addition, BRAF mutations are associated with extrathyroidal invasion, lymph node me...

IntroductionObesity is a global health challenge, with more than 50% of the world´s obese population residing in LMICs. Although adiposity is a well-known major risk factor for noncommunicable diseases (NCDs) such as hypertension, and diabetes mellitus, the delivery of effective NCDs interventions is still a challenge to health systems. About 85% of the NCDs premature deaths occur in LMICs. Obesity is more prevalent in women than men, however the bu...

Objective: The definitive treatment of primary hyperparathyroidism (PPH) is the removal of the affected gland(s). However, its localization can be complicated. The usefulness of 18F-Choline PET-CT versus classical techniques is unknown. The aim of this study was to evaluate the results of 18F-Choline PET-CT in the detection of hyperfunctioning parathyroid tissue with respect to conventional imaging tests and to analyze the relationship between its findings and the levels of ca...

Aims: Charcot foot (CF) is a rare complication of T2DM, progressively leads to bone deformities of the lower extremities. The aim of this study was to record baseline characteristics of patients with CF.Patients and methods: A multicenter retrospective cohort study (n=774), including all patients diagnosed with CF from eight Diabetic Foot Clinics in 6 countries between 01/01/1996 and 31/12/2022, was performed. Data regarding duration and complic...

Silent corticotroph tumors (SCT) represent a distinct subtype of pituitary tumors (PT) known for their potential aggressiveness, surpassing other silent PTs like gonadotroph tumors (SGT). Despite their aggressive clinical behavior, the mechanisms underlying their aggressiveness remain unclear. Recent studies in various cancers, such as breast cancer, have implicated the IGF1 axis in the presence of metastases. This study aims to investigate some components of the somatotroph a...

Introduction: Evidence suggests that, for the same mean glucose level, protein glycation may be different and that this may have an impact on the occurrence of complications. We currently have GMI that estimates mean glucose measured with the FreeStyle Libre 2 and HbA1c determined in the laboratory.Objectives: To analyse the proportion of “rapid glycaemic” patients in our clinical setting (HbA1c-GMI>0.5) and to assess the prevalence of micr...

Introduction and objectives: Diabetic ketoacidosis (DKA) is a severe acute complication of Diabetes Mellitus (DM) and may require hospital admission. Our aim was to compare the characteristics of DKA occurring in patients with autoimmune DM (AMD) and type 2 DM (DM2) in our setting.Methods: Retrospective observational study. Patients with AMD and DM2 admitted for DKA at the Hospital Universitario San Cecilio de Granada between January 2019 and December 20...